Zolpidem Clinical Studies

Before a pharmaceutical company applies for the approval of a medication intended for human use, it is only natural for them to conduct clinical studies. This way, the company can truly observe the effectivity as well as the possible side effects patients might experience while taking the medication. In the case of Zolpidem, there were numerous clinical studies conducted.

Clinical Studies on Efficacy

Zolpidem is actually designed to treat insomnia on a short-term capacity. Clinical studies showed a decline in efficacy if used longer than six weeks. A study of patients taking this medication for 35 days revealed decreased sleep latency.  But there were also trials where patients took the medication for as long as 180 days. Those trials confirmed that Zolpidem is really effective in initiating sleep but not as much in terms of maintaining sleep

Special studies conducted where patients are elderly individuals showed that some populations were sensitive to Zolpidem which means lower dosage should be given. Meanwhile, patients with hepatic and renal insufficiency have trouble clearing out the medication from their system. Based on these studies, recommended adult dosage has been set at one 5mg tablet before going to bed.

Clinical Studies on Side Effects

There were human trials conducted which reported the common side effects most patients would experience when taking Zolpidem including drowsiness and dizziness. But there are also users of Zolpidem who reported incidence of walking, binge eating, having sex, talking, driving and other activities while sleeping. These incidences where reported to have occurred during the first time the patients took the medication or after a couple of days upon starting.

Referred to as “automatism”, where the individual performed tasks automatically just like when they are awake, it is possibly the most dangerous of all Zolpidem side effects. In Australia, this medication was reviewed by the Adverse Drug Reactions Advisory after numerous reports of sleepwalking incidents.  To date, no single clinical study has confirmed these adverse side effects.

Zolpidem Benefits Outweigh the Risks

Despite these reports on the Zolpidem side effects, this medication does more good than harm.  It is still the most prescribed medication for insomnia and is generally safe. If you are worried about the results of these clinical studies, you can always speak to your doctor about it.

Better yet, you can choose to have a friend or another family member stay with you during the first week you are taking the medication. It would also be best if you look at the warnings and precautions leaflet which comes with Zolpidem.

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